Play stops working

When Play is pressed, Play is selected in the Transport menu, or the timeline is double-clicked, the Play button highlights, but the song does not play. To fix this, I have to shutdown and restart n-Track. Up until then, it appears to work normally. Any ideas? This is really annoying when you’re focussed on recording and editing, and you have to break that focus to fool with restarting.

Do you have some effect loaded?
What are buffers?
Have you tried to uninstall, reinstall n-track.?